NEUROGENIC SEXUAL DYSFUNCTION

This article is a systematic review on the topic of neurogenic sexual dysfunction. A systematic evaluation of the English-language literature up to 2024 was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The literature review focused on the following areas: sexual function regulation, neurogenic sexual dysfunction, and neurogenic erectile dysfunction. The review demonstrated that in patients with central nervous system (CNS) disorders, neurological and urological diagnostics are recommended before initiating treatment for sexual dysfunction. The specific diagnostic methods for neurogenic sexual dysfunction were identified. The latest scientific data on sexual function regulation in both genders was summarized. The article listed the main therapeutic approaches to managing sexual dysfunction, including experimental techniques. The rehabilitation strategies for sexual function in patients with neurological pathology are discussed, with an emphasis on the key therapeutic methods. Despite the fact that sexual dysfunction is a significant issue for patients with CNS disorders, high-quality evidence-based studies are exceedingly rare and mostly limited to data on the efficacy of phosphodiesterase type 5 inhibitors (PDE5Is) for the treatment of erectile dysfunction. Well-designed prospective studies for both genders are urgently needed to provide a more comprehensive understanding and effective management of sexual dysfunction in this patient population.