Evaluating gait and postural responses to subthalamic stimulation and levodopa: A prospective study using wearable technology
Our findings suggest positive effects of stimulation and levodopa on gait and postural parameters, with STN-DBS demonstrating superior efficacy in enhancing gait speed, stride length, and turning. However, gait variability remains unaddressed by current therapies, highlighting the need for novel treatments targeting regions beyond the basal ganglia.
Authors
- Lorenzo Chiari (ORCID: https://orcid.org/0000-0002-2318-4370)
- Luca Palmerini (ORCID: https://orcid.org/0000-0003-4758-662X)
- Saverio Ranciati (ORCID: https://orcid.org/0000-0001-7880-9465)
- Ilaria Cani (ORCID: https://orcid.org/0000-0002-9189-1982)
- Ilaria D’Ascanio (ORCID: https://orcid.org/0009-0000-1568-7149)
- Paolo Mantovani (ORCID: https://orcid.org/0000-0002-0036-2509)
- Giovanna Lopane (ORCID: https://orcid.org/0000-0002-3383-0516)
- Giovanna Calandra–Buonaura (ORCID: https://orcid.org/0000-0002-9447-3532)
- Alfredo Conti (ORCID: https://orcid.org/0000-0002-9408-2662)
- Giulia Giannini (ORCID: https://orcid.org/0000-0002-0499-3236)
- Luca Baldelli (ORCID: https://orcid.org/0000-0003-3666-1735)
- Pietro Cortelli (ORCID: https://orcid.org/0000-0002-3633-8818)
Institutions
- Istituto delle Scienze Neurologiche di Bologna (IT)
- University of Bologna (IT)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1111/ene.16580
- Citations
- 4
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.48