5-Bromo-N′-(2-oxoindolin-3-ylidene)furan-2-carbohydrazide
5-Bromo-N′-(2-oxoindolin-3-ylidene)furan-2-carbohydrazide (1) was successfully synthesized in 79.4% yield by reaction of isatin with 5-bromofuran-2-carbohydrazide in acidic conditions under reflux. The structure of synthesized compound 1 was confirmed by 1H and 13C NMR, FTIR, and HRMS spectrometers. It is necessary to evaluate compound 1 as an anti-inflammatory agent.
Authors
- Arif Fadlan (ORCID: https://orcid.org/0000-0002-6138-4015)
- Mardi Santoso (ORCID: https://orcid.org/0000-0003-0636-8386)
- Nur Pasca Aijijiyah (ORCID: https://orcid.org/0000-0001-8332-6732)
- Sri Ningsih (ORCID: https://orcid.org/0000-0002-6139-7625)
Institutions
- Sepuluh Nopember Institute of Technology (ID)
- National Research and Innovation Agency (ID)
Publication Details
- Journal
- Molbank
- Published
- 2024-12-19
- DOI
- https://doi.org/10.3390/m1941
- Primary Topic
- Synthesis and Reactions of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Badan Riset dan Inovasi Nasional
- Lembaga Pengelola Dana Pendidikan