Botanical Bounty: Exploring Aphrodisiac Drug Discovery and Development from Nature's Pharmacy

Ayurveda, Siddha, and Unani are some important traditional healing systems of India having long back evidence-based rejuvenation therapies addressing various infertility and reproductive disorders. Surprisingly, the United Nations has revealed data on infertility that show that it affects around one in every six individuals, highlighting the utmost importance of actively questioning and confronting the misunderstanding and lack of discussion related to infertility. Even though allopathic drugs like Clomiphene citrate, Anastrozole, Letrozole, Human Chronic Gonadotropin (hCG), and Human Menopausal Gonadotropin (hPG) are available on the market, there are a range of traditional and indigenous medical techniques that have been used for millennia to promote and cure health, including Ayurveda, Siddha, and Unani to deliver safe and potent drugs having reproductive rejuvenation with proven evidence. Various botanicals are proven to heal both male and female infertility issues with clinical evidence due to the presence of various potent phytochemicals. Hence this review critically assesses the evidence-based literature focused on the mapping of botanical sources, phytochemicals, reproductive pharmacology, and their clinical evidence.