Organocatalytic enantioselective [2 + 2] cycloadditions towards chiral fused α-trifluoromethyl azetidines

Herein, we report straightforward access to chiral fused α-trifluoromethyl azetidines via organocatalytic asymmetric [2 + 2] cycloadditions. This method is characterized by mild reaction conditions, high efficiency, and excellent stereoselectivities.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2024-12-19
DOI
https://doi.org/10.1039/d4qo01942c
Citations
11
Primary Topic
Fluorine in Organic Chemistry
Type
article
Field-Weighted Citation Impact
2.29
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article

Organocatalytic enantioselective [2 + 2] cycloadditions towards chiral fused α-trifluoromethyl azetidines

Tianli Wang, S. Zhang, Zhipeng Xu, Jia‐Hong Wu et al.
11 citations
Organic Chemistry Frontiers
Fluorine in Organic Chemistry
2.29
article

Organocatalytic enantioselective [2 + 2] cycloadditions towards chiral fused α-trifluoromethyl azetidines

Tianli Wang, S. Zhang, Zhipeng Xu, Jia‐Hong Wu, Siqiang Fang, Jianke Pan, Xingjie Luo
article en
11 citations

Abstract

Herein, we report straightforward access to chiral fused α-trifluoromethyl azetidines via organocatalytic asymmetric [2 + 2] cycloadditions. This method is characterized by mild reaction conditions, high efficiency, and excellent stereoselectivities.

Organic Chemistry FrontiersVol. 12(4)
Sichuan University (CN)
Affordable and clean energy
Openalex Percentile: Top 12%
Fluorine in Organic Chemistry
2.29
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