Efficacy and Safety Evaluation of Immune Checkpoint Inhibitors in Combination With Chemotherapy for Extensive Small Cell Lung Cancer: Real‐World Evidence

The primary distinction between these treatments was observed in the management of patients with brain metastasis. The literature lacks comparative studies on the effects of first-line ICI treatment on the central nervous system, rendering our findings significant in clinical practice. Despite the retrospective nature of this study and the potential for various biases, we recommend the preferential use of Atezo + CE in patients with brain metastasis to potentially enhance prognosis.

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Publication Details

Journal
Cancer Medicine
Published
2024-12-01
DOI
https://doi.org/10.1002/cam4.70480
Citations
3
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.85
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article

Efficacy and Safety Evaluation of Immune Checkpoint Inhibitors in Combination With Chemotherapy for Extensive Small Cell Lung Cancer: Real‐World Evidence

Hiroshige Yoshioka, Yukiko Okuno, Utae Katsushima, Yuta Yamanaka et al.
3 citations
Cancer Medicine
Lung Cancer Research Studies
0.85
article

Efficacy and Safety Evaluation of Immune Checkpoint Inhibitors in Combination With Chemotherapy for Extensive Small Cell Lung Cancer: Real‐World Evidence

Hiroshige Yoshioka, Yukiko Okuno, Utae Katsushima, Yuta Yamanaka, Yuki Takeyasu, Yuko Sanada, Takayasu Kurata, Tatsuki Ikoma, Keisuke Kamisako, Yuta Okazaki, Kentaro Nakanishi, K Yoshida
article en
3 citations

Abstract

The primary distinction between these treatments was observed in the management of patients with brain metastasis. The literature lacks comparative studies on the effects of first-line ICI treatment on the central nervous system, rendering our findings significant in clinical practice. Despite the retrospective nature of this study and the potential for various biases, we recommend the preferential use of Atezo + CE in patients with brain metastasis to potentially enhance prognosis.

Cancer MedicineVol. 13(24)
Kansai Medical University (JP)
Good health and well-being
Openalex Percentile: Top 21%
Lung Cancer Research Studies
0.85
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