Proapoptotic role of CDK1 in overcoming paclitaxel resistance in ovarian cancer cells in response to combined treatment with paclitaxel and duloxetine
Taken together, switching CDK1 to a proapoptotic role through the combination of paclitaxel and duloxetine could overcome paclitaxel resistance in ovarian cancer cells, providing promising therapeutic strategies for treating paclitaxel-resistant ovarian cancer.
Authors
- Hyunggee Kim (ORCID: https://orcid.org/0000-0002-5164-1663)
- In‐Chul Park (ORCID: https://orcid.org/0000-0003-0619-5198)
- Chan Sub Park
- Seunghee Bae (ORCID: https://orcid.org/0000-0001-9114-3063)
- Se‐Lim Kim
- Gyeongmi Kim (ORCID: https://orcid.org/0000-0002-4133-6032)
- Se‐Kyeong Jang (ORCID: https://orcid.org/0000-0002-5444-7161)
- Jae Ho Lee (ORCID: https://orcid.org/0000-0002-1556-3485)
- Hyun‐Ah Kim (ORCID: https://orcid.org/0000-0001-9713-2605)
- Min-Ki Seong
- Hyeon-Ok Jin
- Se Hee Ahn
Institutions
- Korea University (KR)
- Konkuk University (KR)
- Korea Institute of Radiological and Medical Sciences (KR)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s12935-024-03607-8
- Citations
- 5
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- National Research Foundation
- National Research Foundation of Korea
- Korea Institute of Radiological and Medical Sciences
- Ministry of Science and ICT, South Korea