Guanylate-binding protein 5-mediated autophagy can promote the clearance of intracellular F. nucleatum in dental pulp cells during pulpitis
IFN-γ-mediated GBP5 overexpression in HDPCs during F. nucleatum infection exerts an anti-microbial function through autophagy activation.
Authors
- Bo Yang (ORCID: https://orcid.org/0000-0003-4608-6957)
- Xinzhu Li (ORCID: https://orcid.org/0000-0002-6459-793X)
- Xiaojun Yang (ORCID: https://orcid.org/0000-0003-3280-7725)
- Jin Hou (ORCID: https://orcid.org/0000-0003-4004-9071)
- Minchun Huang (ORCID: https://orcid.org/0009-0004-4603-9661)
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s12903-024-05295-2
- Citations
- 2
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Project