The impact of age, sex, and gender on polypharmacy and potential prescribing cascades: Lessons from five databases
Older adults with lower SES experienced polypharmacy or co-prescribing suggesting a prescribing cascade more frequently than those with higher SES. Within the lower SES groups, females more frequently than males had evidence of co-prescribing suggesting a prescribing cascade. Considering the role of sex and gender-related sociocultural factors may help to better understand some contributors to polypharmacy and prescribing cascades. The research applications are highlighted in our five lessons learned.
Authors
- Parya Borhani (ORCID: https://orcid.org/0009-0007-6260-2102)
- Lisa McCarthy (ORCID: https://orcid.org/0000-0001-9087-1077)
- Antonio Cherubini (ORCID: https://orcid.org/0000-0003-0261-9897)
- Shelley A. Sternberg (ORCID: https://orcid.org/0000-0002-0375-6319)
- Denis O’Mahony (ORCID: https://orcid.org/0000-0003-2236-5222)
- Vasily Giannakeas (ORCID: https://orcid.org/0000-0003-2924-8723)
- Paula A. Rochon (ORCID: https://orcid.org/0000-0002-5973-4151)
- Graziano Onder (ORCID: https://orcid.org/0000-0003-3400-4491)
- Kieran Dalton
- Wei Wu (ORCID: https://orcid.org/0000-0002-8601-9161)
- Rachel Savage (ORCID: https://orcid.org/0000-0002-2746-373X)
- Robín Masón (ORCID: https://orcid.org/0000-0003-3143-6811)
- A. Giancola
- Mirko Petrović (ORCID: https://orcid.org/0000-0002-7506-8646)
- Joyce Li (ORCID: https://orcid.org/0000-0001-8112-2701)
- Jerry H. Gurwitz (ORCID: https://orcid.org/0000-0003-1630-8213)
- Altea Kthupi
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Marche Polytechnic University (IT)
- University of Massachusetts Chan Medical School (US)
- University of Toronto (CA)
- University College Cork (IE)
- Trillium Health Centre (CA)
- Ghent University Hospital (BE)
- Women's College Hospital (CA)
- Agostino Gemelli University Polyclinic (IT)
- Maccabi Healthcare Services (IL)
- Public Health Ontario (CA)
- Institute for Clinical Evaluative Sciences (CA)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto Nazionale di Riposo e Cura per Anziani (IT)
Publication Details
- Journal
- Journal of the American Geriatrics Society
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1111/jgs.19282
- Citations
- 5
- Primary Topic
- Pharmaceutical Practices and Patient Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Irish Research Council
- Ministero della Salute
- Women's College Hospital
- Università Cattolica del Sacro Cuore
- Canadian Institutes of Health Research
- Institute of Gender and Health