Induction of Fc-dependent functional antibodies against different variants of SARS-CoV-2 varies by vaccine type and prior infection
Hybrid immunity, from combined natural exposure and vaccination, generates strong Fc-mediated antibody functions which may contribute to immunity against evolving SARS-CoV-2 variants. Understanding determinants of Fc-mediated functions may enable future vaccines with greater efficacy against different variants.
Authors
- P. Mark Hogarth (ORCID: https://orcid.org/0000-0002-0360-7890)
- Pantelis Poumbourios (ORCID: https://orcid.org/0000-0002-2772-1962)
- Heidi E. Drummer (ORCID: https://orcid.org/0000-0002-0042-6277)
- Alexander W. Harris
- Isabel Bouzas
- Luís Cristóvão Pôrto (ORCID: https://orcid.org/0000-0003-1499-1821)
- Clarissa Valim (ORCID: https://orcid.org/0000-0001-9621-203X)
- D. Herbert Opi (ORCID: https://orcid.org/0000-0002-4589-4365)
- Bruce D. Wines (ORCID: https://orcid.org/0000-0002-4108-375X)
- Wen Shi Lee (ORCID: https://orcid.org/0000-0001-7285-4054)
- Liriye Kurtovic (ORCID: https://orcid.org/0000-0001-8594-0031)
- James G. Beeson (ORCID: https://orcid.org/0000-0002-1018-7898)
- Jeane Nogueira
Institutions
- Boston University (US)
- Burnet Institute (AU)
- The University of Melbourne (AU)
- Universidade do Estado do Rio de Janeiro (BR)
- Peter Doherty Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Communications Medicine
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1038/s43856-024-00686-6
- Citations
- 2
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- Burnet Institute
- Universidade do Estado do Rio de Janeiro
- Medical Research Council
- National Health and Medical Research Council