Integrating C–H activation/2-fold annulation: a modular access to heteroaryl-tethered oxazoloisoquinolinones
A cascade C-H activation/2-fold annulation of 2-aryloxazolines with pyridotriazoles has been achieved employing Rh-catalysis to afford heteroaryl-tethered oxazoloisoquinolinones. The synergistic annulations, functional group tolerance, and late-stage skeletal editing of the bioactive scaffolds are the salient practical features.
Authors
- Tharmalingam Punniyamurthy (ORCID: https://orcid.org/0000-0003-4696-8896)
- Tripti Paul (ORCID: https://orcid.org/0000-0001-9240-7745)
- Shubhajit Basak (ORCID: https://orcid.org/0000-0002-0315-4158)
- Maniya V. Nanjegowda (ORCID: https://orcid.org/0009-0006-9015-9745)
Institutions
- Indian Institute of Technology Guwahati (IN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1039/d4cc06123c
- Citations
- 7
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.75