Molecular Differences in Pancreatic Ductal Adenocarcinomas from Black versus White Patients
By analyzing the records of patients with pancreatic cancer in the Tempus multimodal database, we identified genomic mutations and PD-L1 overexpression occurred more frequently in Black patients compared with their White counterparts. These molecular features may contribute to racial disparities in pancreatic cancer.
Authors
- Saurabh Mandal (ORCID: https://orcid.org/0000-0003-1799-282X)
- Adam J. Hockenberry (ORCID: https://orcid.org/0000-0001-9476-0104)
- Swathi Sridhar
- Melissa C. Stoppler
- Ling Huang (ORCID: https://orcid.org/0000-0001-8855-788X)
- Howard C. Crawford (ORCID: https://orcid.org/0000-0001-9360-3019)
- Emily A. Teslow (ORCID: https://orcid.org/0000-0001-5506-1749)
- Albert M. Levin (ORCID: https://orcid.org/0000-0002-6993-1669)
- Yingying Yu (ORCID: https://orcid.org/0009-0004-7828-8646)
- Minxuan Huang
Institutions
- Henry Ford Health System (US)
- Henry Ford Hospital (US)
- Michigan United (US)
- Tempus Labs (United States) (US)
- Michigan State University (US)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1158/2767-9764.crc-24-0376
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Memorial Sloan-Kettering Cancer Center
- National Cancer Institute
- National Institute on Minority Health and Health Disparities