Comparison of Shared Class I HLA-Bound Noncanonical Neoepitopes between Normal and Neoplastic Tissues of Pancreatic Adenocarcinoma
The shared noncanonical neoepitopes identified in this study offer promising candidates for vaccine and T-cell therapy development, potentially providing new avenues for immunotherapy in PDAC. See related commentary by Yuan et al., p. 1821.
Authors
- Yingkuan Shao (ORCID: https://orcid.org/0000-0001-9683-5691)
- Tengyi Zhang
- Betul Celiker
- Jessica Gai
- Chunyu Wang (ORCID: https://orcid.org/0000-0001-5165-7959)
- C. Mark Hill
- Lei Zheng (ORCID: https://orcid.org/0000-0003-4163-2541)
Institutions
- Johns Hopkins University (US)
- Bristol-Myers Squibb (Germany) (DE)
- Rensselaer Polytechnic Institute (US)
- Johns Hopkins Medicine (US)
- University of Chicago (US)
- Bristol-Myers Squibb (United States) (US)
- Zhejiang Cancer Hospital (CN)
- Sidney Kimmel Cancer Center (US)
- Sidney Kimmel Comprehensive Cancer Center (US)
- Zhejiang University (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-2251
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Bristol-Myers Squibb
- Johns Hopkins University
- National Institutes of Health