The Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP): Statistical Methods Planned in the Bayesian, Adaptive, Duration Finding Trial
The P-ICECAP trial aims to identify the shortest cooling duration that provides the maximum treatment effect for pediatric OHCA patients. The adaptive design allows for flexibility and efficiency in handling various clinical scenarios, potentially transforming pediatric cardiac arrest care by optimizing hypothermia treatment protocols.
Authors
- Alexis Topjian (ORCID: https://orcid.org/0000-0001-7855-8627)
- Sharon D. Yeatts (ORCID: https://orcid.org/0000-0001-9235-0670)
- William J. Meurer (ORCID: https://orcid.org/0000-0002-1158-5302)
- Richard Holubkov (ORCID: https://orcid.org/0000-0003-0431-3381)
- Frank W. Moler
- Kent Page (ORCID: https://orcid.org/0000-0001-9731-6607)
- Robert G. Clevenger (ORCID: https://orcid.org/0009-0001-7075-0312)
- John M. VanBuren (ORCID: https://orcid.org/0000-0003-1350-5764)
Institutions
- Children's Hospital of Philadelphia (US)
- Medical University of South Carolina (US)
- University of Utah (US)
- University of Michigan (US)
- Levine Cancer Institute (US)
Publication Details
- Journal
- Pediatric Critical Care Medicine
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1097/pcc.0000000000003667
- Citations
- 4
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 2.76