Hepcidin inhibits hepatocyte apoptosis through the PERK pathway in acute liver injury and fibrosis

Hepcidin inhibits hepatocyte apoptosis through suppression of the PERK pathway, highlighting its protective role in liver fibrosis and identifying a potential therapeutic target for the treatment of liver fibrosis.

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Publication Details

Journal
Hepatology Communications
Published
2024-12-19
DOI
https://doi.org/10.1097/hc9.0000000000000604
Citations
2
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
0.91

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article

Hepcidin inhibits hepatocyte apoptosis through the PERK pathway in acute liver injury and fibrosis

Changying Li, Tianhui Liu, Xinyan Zhao, Xiaoli Huang et al.
2 citations
Hepatology Communications
Iron Metabolism and Disorders
0.91
article

Hepcidin inhibits hepatocyte apoptosis through the PERK pathway in acute liver injury and fibrosis

Changying Li, Tianhui Liu, Xinyan Zhao, Xiaoli Huang, Wei Chen, Min Cong, Yingying Liu, Ping Wang, Ming Gao, Weihua Zhao, Xu Fan, G Pang
article en
2 citations

Abstract

Hepcidin inhibits hepatocyte apoptosis through suppression of the PERK pathway, highlighting its protective role in liver fibrosis and identifying a potential therapeutic target for the treatment of liver fibrosis.

Hepatology CommunicationsVol. 9(1)
Capital Medical University (CN), Chinese Academy of Sciences (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), National Clinical Research Center for Digestive Diseases (CN), Research Center for Eco-Environmental Sciences (CN), Beijing Friendship Hospital (CN), Beijing Hua Xin Hospital (CN), University of Chinese Academy of Sciences (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 21%
Iron Metabolism and Disorders
0.91
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