Adult-onset hypophosphatasia diagnosed after consecutive tooth loss during orthodontic treatment: a case report
This case highlights the significance of including adult hypophosphatasia in the differential diagnosis for obscure dental complications arising during orthodontic procedures, particularly in Asian patients where certain ALPL variants may be more prevalent. Effective diagnosis and management of adult hypophosphatasia necessitate collaboration between orthodontic practitioners and medical specialists. Improved awareness and a multidisciplinary approach are crucial for timely diagnosis and successful intervention.
Authors
- Hideo Tanaka (ORCID: https://orcid.org/0000-0001-9033-0035)
- K. Ide
- Takeru Nabeta (ORCID: https://orcid.org/0000-0003-4671-7667)
- Edward Hosea Ntege (ORCID: https://orcid.org/0000-0003-2388-4542)
- Makoto Murahashi
- Yusuke Shimizu (ORCID: https://orcid.org/0000-0002-2528-2003)
- Shusuke Tokuchi
- Hiroyuki Nakamura (ORCID: https://orcid.org/0000-0002-2524-3063)
- Nobuyuki Maruyama (ORCID: https://orcid.org/0000-0002-1695-5077)
- Toshihiro Kawano
- Risako Suzuki
- Mirei Takai-Nabeta
Institutions
- University of the Ryukyus (JP)
Publication Details
- Journal
- Journal of Medical Case Reports
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s13256-024-04948-8
- Citations
- 2
- Primary Topic
- Alkaline Phosphatase Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- Japan Society for the Promotion of Science