Stimulated Raman Histology and Artificial Intelligence Provide Near Real-Time Interpretation of Radical Prostatectomy Surgical Margins
SRH demonstrates potential as a valuable tool for real-time intraoperative assessment of surgical margins during RALP. This technique may improve nerve-sparing surgery and facilitate decision-making for further resection, reducing the risk of positive surgical margins and minimizing the risk of recurrence. Further studies with larger cohorts and longer follow-up periods are warranted to confirm the benefits of SRH in RALP.
Authors
- Christian W. Freudiger
- Jonathan Melamed (ORCID: https://orcid.org/0000-0003-2844-7990)
- Feng Deng (ORCID: https://orcid.org/0000-0001-9837-4227)
- James Steven Wysock (ORCID: https://orcid.org/0000-0002-7669-0947)
- Adrian Ion‐Mărgineanu (ORCID: https://orcid.org/0000-0003-3788-2257)
- Lea Lough (ORCID: https://orcid.org/0000-0001-8175-1786)
- Miles P. Mannas (ORCID: https://orcid.org/0000-0002-7706-3830)
- William C. Huang (ORCID: https://orcid.org/0000-0001-5261-0650)
- Samir S. Taneja (ORCID: https://orcid.org/0000-0003-0887-8259)
- Daniel A. Orringer (ORCID: https://orcid.org/0000-0001-6427-8376)
- Steve Pastore
- Deepthi Hoskoppal (ORCID: https://orcid.org/0000-0002-5133-3054)
- Weiwei Huang (ORCID: https://orcid.org/0000-0002-9947-4083)
- Derek Jones (ORCID: https://orcid.org/0000-0002-9436-8951)
Institutions
- University of British Columbia (CA)
- NYU Langone Health (US)
- Invenio Imaging (United States) (US)
Publication Details
- Journal
- The Journal of Urology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1097/ju.0000000000004393
- Citations
- 6
- Primary Topic
- Spectroscopy Techniques in Biomedical and Chemical Research
- Type
- article
- Field-Weighted Citation Impact
- 9.80