Developmental gene expression in skull-base chordomas and chondrosarcomas
As chordoma patients demonstrate a worse prognosis compared to chondrosarcoma patients, the differential expression of chordin, HOXA5 and ACAN and CD24 could be relevant for the pathophysiology of chordomas and may have diagnostic and treatment value. Further study on role of these genes in tumorigenesis is therefore warranted.
Authors
- Youssef Yakkioui (ORCID: https://orcid.org/0000-0002-2190-7432)
- Koos E. Hovinga (ORCID: https://orcid.org/0000-0002-1415-8189)
- Govert Hoogland
- Thomas Vaessen (ORCID: https://orcid.org/0000-0002-9300-3117)
- Yasin Temel (ORCID: https://orcid.org/0000-0002-3589-5604)
- Cas Vanderheijden (ORCID: https://orcid.org/0000-0003-4275-8808)
- Remco Santegoeds
Institutions
- Maastricht University Medical Centre (NL)
- University Medical Center (US)
- Maastricht University (NL)
- Noordwest Ziekenhuisgroep (NL)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2024-12-17
- DOI
- https://doi.org/10.1007/s11060-024-04913-x
- Citations
- 2
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.94