Disseminated intravascular coagulopathy and subsequent kidney injury requiring dialysis after a second-trimester dilation and evacuation procedure.

A primigravida in her 20s with a body mass index of 18 underwent dilation and evacuation at 22 and 4 weeks gestational age to manage an intrauterine fetal demise (IUFD) that had occurred 14 days ago. Hypoxaemia and vaginal bleeding developed 90 min postprocedure. Investigations demonstrated changes compatible with acute respiratory distress syndrome secondary to disseminated intravascular coagulopathy which was managed with intubation, mechanical ventilation and transfusion of blood products. Although the coagulopathy and respiratory failure resolved, severe acute kidney injury ensued resulting in acute tubular necrosis, severe labial oedema and the need for prolonged support with haemodialysis until kidney recovery 7 weeks later.

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Publication Details

Journal
Carolina Digital Repository (University of North Carolina at Chapel Hill)
Published
2024-12-17
DOI
https://doi.org/10.17615/80mq-7t48
Primary Topic
Maternal and fetal healthcare
Type
article
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article

Disseminated intravascular coagulopathy and subsequent kidney injury requiring dialysis after a second-trimester dilation and evacuation procedure.

Clay A. Block, Shilpa Darivemula, Amy E. Paris, Gurinder Luthra
Carolina Digital Repository (University of North Carolina at Chapel Hill)
Maternal and fetal healthcare
article

Disseminated intravascular coagulopathy and subsequent kidney injury requiring dialysis after a second-trimester dilation and evacuation procedure.

Clay A. Block, Shilpa Darivemula, Amy E. Paris, Gurinder Luthra
article en

Abstract

A primigravida in her 20s with a body mass index of 18 underwent dilation and evacuation at 22 and 4 weeks gestational age to manage an intrauterine fetal demise (IUFD) that had occurred 14 days ago. Hypoxaemia and vaginal bleeding developed 90 min postprocedure. Investigations demonstrated changes compatible with acute respiratory distress syndrome secondary to disseminated intravascular coagulopathy which was managed with intubation, mechanical ventilation and transfusion of blood products. Although the coagulopathy and respiratory failure resolved, severe acute kidney injury ensued resulting in acute tubular necrosis, severe labial oedema and the need for prolonged support with haemodialysis until kidney recovery 7 weeks later.

Carolina Digital Repository (University of North Carolina at Chapel Hill)
University of North Carolina at Chapel Hill (US)
Good health and well-being
Openalex Percentile: Top 64%
Maternal and fetal healthcare
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Disseminated intravascular coagulopathy and subsequent kidney injury requiring dialysis after a second-trimester dilation and evacuation procedure. — Clay A. Block, Shilpa Darivemula, et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill) (2024) | TGRS Research Map | TGRS