A single-center experience of central nervous system tumors in children under three years old
GTR remains the cornerstone of treatment for children (≤3 years) with CNS tumors, except for optic glioma, diffuse midline glioma, and germinoma. The interactive factor (extent of resection × CNS WHO grade) and Ki-67 LI are the most significant factors affecting OS. The implementation of preoperative neoadjuvant chemotherapy and early postoperative chemotherapy may enhance prognosis.
Authors
- Yuqi Zhang (ORCID: https://orcid.org/0000-0001-8482-1989)
- Junhua Wang (ORCID: https://orcid.org/0000-0002-6110-3711)
- Zhihua Zhang (ORCID: https://orcid.org/0000-0002-9387-7308)
- Zhimin Huang (ORCID: https://orcid.org/0000-0003-1251-0529)
- Xuping Wang (ORCID: https://orcid.org/0000-0003-3431-6508)
Institutions
- Qilu Hospital of Shandong University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2024-12-18
- DOI
- https://doi.org/10.3389/fped.2024.1441016
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.44
Funders
- Tsinghua University