The Histopathology and Treatment Strategies of Adenocarcinoma

Adenocarcinoma is a cancer of glandular tissue and, therefore, poses considerable problems for diagnosis and treatment. The diverse nature of this cancer mandates a proper staging system for the guidance of treatment approaches for better patient outcomes. Advances in molecular biology, histopathology, and immunohistochemistry in recent years have contributed significantly to our understanding of adenocarcinoma, especially as it appears in the lung and gastrointestinal systems. This review attempts to synthesize the present knowledge about the classification of adenocarcinoma and the various treatment modalities with more stress on the clinical applications, while at the same time indicating areas that are not known and where further research should be directed.