Uniparental disomy (UPD) exclusion in embryos following Preimplantation Genetic Testing for Structural Rearrangements (PGT-SR)
Integrating STR-based UPD screening within PGT-SR workflows is a reliable and cost-effective strategy that enhances embryo selection and mitigates the risk of imprinting disorders. This approach improves reproductive outcomes for families with chromosomal rearrangements, offering a practical advancement in assisted reproduction.
Authors
- Danilo Cristofano
- Antonella Viola (ORCID: https://orcid.org/0000-0002-0125-9271)
- Katia Margiotti (ORCID: https://orcid.org/0000-0003-0432-1525)
- Mario Montanino Oliva (ORCID: https://orcid.org/0000-0001-8676-1465)
- Maria Antonietta Barone
- Giovanna Buonomo
- Alvaro Mesoraca (ORCID: https://orcid.org/0009-0000-6954-6392)
- Marco Fabiani (ORCID: https://orcid.org/0000-0002-8763-0114)
- Concetta De Pasquale (ORCID: https://orcid.org/0000-0003-4692-0980)
- Antonella Cima
- Claudio Giorlandino (ORCID: https://orcid.org/0000-0002-8448-7260)
- Assunta Lippa
- Francesco Libotte (ORCID: https://orcid.org/0000-0001-9050-324X)
- Chiara Alì
- Costanza Zangheri
Institutions
- Marconi University (IT)
- ALTA (Italy) (IT)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1007/s10815-024-03352-x
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 0.00