APPLICATION OF VETOM 1.1 PROBIOTIC FOR PREVENTION OF HEPATIC PATHOLOGIES IN SERVICE DOGS

The effect of probiotic product Vetom 1.1 on blood biochemical indices of German Shepherd service dogs was studied. The relevance of the study is due to the need for finding new methods of correction of metabolic disorders at liver diseases in dogs. The study involved 12 dogs divided into two groups: trial group (receiving Vetom 1.1) and the control group. The probiotic product was administered daily in a dosage of 2.5 g, and blood sample were taken for testing four times. The results showed that in the trial group the level of total protein decreased mainly due to decreased concentration of globulins showing the recovery of liver function. Creatinine levels in both groups remained stable throughout the study showing no change in kidney function. Urea levels decreased which was due to impaired urea synthesis in liver disease. Uric acid level increased in the trial group which might be due to changes in purine metabolism. Calcium level in the trial group decreased by the second testing but remained stable thereafter showing adaptation of the body. Phosphorus level, on the contrary, increased significantly by the fourth testing showing a positive effect of the probiotic on its metabolism. Triglyceride levels also increased showing improved lipid absorption. The ALT and AST activity increased in both groups, but was lower in the trial group showing less damage to hepatocytes. The creatine kinase levels decreased in both groups excluding the association with cardiac pathology. Thus, Vetom 1.1 probiotic product contributes to the normalization of metabolic processes and improvement of liver condition in service dogs confirming its effectiveness in hepatosis prevention.