IL-17A mediates inflammation-related retinal pigment epithelial cells injury via ERK signaling pathway
IL-17A probably promotes the NaIO<sub>3</sub>-induced RPE cells injury through exacerbating inflammation in terms of retinal microglia activation and inflammatory cytokines release <i>via</i> ERK signaling pathway. Inhibition of IL-17A may be a new potential target for dry AMD treatment.
Authors
- Xiaodong Sun (ORCID: https://orcid.org/0000-0001-7775-2823)
- Minwen Zhou (ORCID: https://orcid.org/0000-0002-3746-2300)
- Yu‐Hong Chen (ORCID: https://orcid.org/0009-0009-8356-0153)
- Huimin Zhong (ORCID: https://orcid.org/0000-0002-1371-6951)
- Xiaoxu Huang (ORCID: https://orcid.org/0000-0002-2631-5284)
- Xiaohuan Zhao (ORCID: https://orcid.org/0000-0001-9109-7909)
Institutions
- Shanghai Jiao Tong University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- International Journal of Ophthalmology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.18240/ijo.2025.01.03
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00