Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia
This comprehensive analysis of AD in elderly individuals using RNA-seq data and NGKD tools revealed multiple differentially regulated pathways, gene signatures, and potential drugs for dementia treatment. These findings highlight the complex molecular mechanisms underlying AD and provide insights into potential therapeutic strategies. Further research is needed to validate these findings and to develop personalized treatment approaches for AD in elderly patients.
Authors
- Peter Natesan Pushparaj (ORCID: https://orcid.org/0000-0001-7574-1880)
- Hind Ali Alkhatabi (ORCID: https://orcid.org/0000-0002-8082-838X)
Institutions
- King Abdulaziz University (SA)
- University of Jeddah (SA)
Publication Details
- Journal
- Heliyon
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e41266
- Citations
- 1
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- University of Jeddah