Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia

This comprehensive analysis of AD in elderly individuals using RNA-seq data and NGKD tools revealed multiple differentially regulated pathways, gene signatures, and potential drugs for dementia treatment. These findings highlight the complex molecular mechanisms underlying AD and provide insights into potential therapeutic strategies. Further research is needed to validate these findings and to develop personalized treatment approaches for AD in elderly patients.

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Publication Details

Journal
Heliyon
Published
2024-12-18
DOI
https://doi.org/10.1016/j.heliyon.2024.e41266
Citations
1
Primary Topic
Bioinformatics and Genomic Networks
Type
article
Field-Weighted Citation Impact
0.23

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article

Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia

Peter Natesan Pushparaj, Hind Ali Alkhatabi
1 citations
Heliyon
Bioinformatics and Genomic Networks
0.23
article

Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia

Peter Natesan Pushparaj, Hind Ali Alkhatabi
article en
1 citations

Abstract

This comprehensive analysis of AD in elderly individuals using RNA-seq data and NGKD tools revealed multiple differentially regulated pathways, gene signatures, and potential drugs for dementia treatment. These findings highlight the complex molecular mechanisms underlying AD and provide insights into potential therapeutic strategies. Further research is needed to validate these findings and to develop personalized treatment approaches for AD in elderly patients.

HeliyonVol. 11(1)
King Abdulaziz University (SA), University of Jeddah (SA)
University of Jeddah
Openalex Percentile: Top 40%
Bioinformatics and Genomic Networks
0.23
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Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia — Peter Natesan Pushparaj, Hind Ali Alkhatabi · Heliyon (2024) | TGRS Research Map | TGRS