Novel axial oxygenator with bevelled shape of priming volume

Abstract Oxygenators are a lifesaving technology used for blood oxygenation and decarboxylation in case of acute respiratory failure, chronic lung disease, and during open-heart surgery. Devices typically consist of a bundle of thousands of fibre membranes in a housing, with gas flowing inside the fibres and blood flowing in the opposite direction outside the fibres. Both ends of the fibre-membranes are fixed with an adhesive to separate gas and blood. The shape of the volume through which the blood flows is determined by the housing of the oxygenator and the internal end surfaces of the fixed ends of the fibre-membrane bundle. The traditional potting process results in a volume shape that is associated with stagnation zones, which are known to promote thrombus formation. In this study, an adapted potting process is proposed which results in a blood compartment with bevelled end faces of the glued bundle parts. Using a numerical study, we have demonstrated that the novel oxygenator design results in optimized flow conditions.

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Publication Details

Journal
Current Directions in Biomedical Engineering
Published
2024-12-01
DOI
https://doi.org/10.1515/cdbme-2024-2065
Citations
1
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.61
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article

Novel axial oxygenator with bevelled shape of priming volume

Benedikt Franke, Leonid Goubergrits
1 citations
Current Directions in Biomedical Engineering
Advanced Radiotherapy Techniques
0.61
article

Novel axial oxygenator with bevelled shape of priming volume

Benedikt Franke, Leonid Goubergrits
article en
1 citations

Abstract

Abstract Oxygenators are a lifesaving technology used for blood oxygenation and decarboxylation in case of acute respiratory failure, chronic lung disease, and during open-heart surgery. Devices typically consist of a bundle of thousands of fibre membranes in a housing, with gas flowing inside the fibres and blood flowing in the opposite direction outside the fibres. Both ends of the fibre-membranes are fixed with an adhesive to separate gas and blood. The shape of the volume through which the blood flows is determined by the housing of the oxygenator and the internal end surfaces of the fixed ends of the fibre-membrane bundle. The traditional potting process results in a volume shape that is associated with stagnation zones, which are known to promote thrombus formation. In this study, an adapted potting process is proposed which results in a blood compartment with bevelled end faces of the glued bundle parts. Using a numerical study, we have demonstrated that the novel oxygenator design results in optimized flow conditions.

Current Directions in Biomedical EngineeringVol. 10(4)
Deutsches Herzzentrum der Charité (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 28%
Advanced Radiotherapy Techniques
0.61
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Novel axial oxygenator with bevelled shape of priming volume — Benedikt Franke, Leonid Goubergrits · Current Directions in Biomedical Engineering (2024) | TGRS Research Map | TGRS