Genomics-informed neuropsychiatric care for neurodevelopmental disorders: Results from a multidisciplinary clinic
A genomics-informed model can provide significant clinical benefits to patients with NDDs, directly affecting management across multiple domains for most diagnosed patients. As precision treatments advance, establishing a genetic diagnosis will be critical for proper management. With the growing number of rare neurogenetic disorders, clinician training should emphasize core principles of genomic medicine over individual syndromes.
Authors
- Charlotte DiStefano (ORCID: https://orcid.org/0000-0003-1927-8590)
- Julián A. Martínez-Agosto (ORCID: https://orcid.org/0000-0001-6776-6949)
- Sunil Mehta (ORCID: https://orcid.org/0000-0003-3020-4939)
- Aaron D. Besterman (ORCID: https://orcid.org/0000-0002-8671-1203)
- Benjamin Schneider (ORCID: https://orcid.org/0000-0002-0187-8873)
- Shafali Jeste (ORCID: https://orcid.org/0000-0003-2955-6902)
- David J. Adams (ORCID: https://orcid.org/0000-0001-9490-0306)
- Rujuta B. Wilson
- Nicole R. Wong
Institutions
- Children's Hospital of Los Angeles (US)
- Johns Hopkins University (US)
- University of California, Los Angeles (US)
- Rady Children's Hospital-San Diego (US)
- SVT Associates (United States) (US)
Publication Details
- Journal
- Genetics in Medicine
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1016/j.gim.2024.101333
- Citations
- 5
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- Health Resources and Services Administration
- Intellectual and Developmental Disabilities Research Center
- National Institute of General Medical Sciences
- National Center for Advancing Translational Sciences
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Clinical and Translational Science Institute, University of California, Los Angeles