Re-analysis of data from cluster randomised trials to explore the impact of model choice on estimates of odds ratios: study protocol
There have been a number of small comparisons of empirical differences between the different approaches to analysis for CRTs. The systematic approach outlined in this protocol will allow a much deeper understanding of when there are important choices around the model approach and in which settings. This will be of importance given the heightened awareness of the importance of estimands and the specification of statistical analysis plans.
Authors
- JA Thompson (ORCID: https://orcid.org/0000-0002-3068-3952)
- Jacqueline Thompson (ORCID: https://orcid.org/0000-0002-9775-361X)
- Karla Hemming (ORCID: https://orcid.org/0000-0002-2226-6550)
- Brennan C Kahan (ORCID: https://orcid.org/0000-0001-9957-0844)
- Jessica Kasza (ORCID: https://orcid.org/0000-0002-8940-0136)
- Andrew J Copas (ORCID: https://orcid.org/0000-0001-8968-5963)
- Sam Watson (ORCID: https://orcid.org/0000-0002-8972-769X)
- Monica Taljaard (ORCID: https://orcid.org/0000-0002-3978-8961)
Institutions
- University of Ottawa (CA)
- Ottawa Hospital (CA)
- London School of Hygiene & Tropical Medicine (GB)
- MRC Clinical Trials Unit at UCL (GB)
- Ottawa Hospital Research Institute (CA)
- University College London (GB)
- Monash University (AU)
- University of Birmingham (GB)
Publication Details
- Journal
- Trials
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13063-024-08653-1
- Citations
- 4
- Primary Topic
- Statistical Methods and Bayesian Inference
- Type
- article
- Field-Weighted Citation Impact
- 2.84
Funders
- National Institute for Health and Care Research
- Department of Health and Social Care
- Medical Research Council