Efficacy of Nirmatrelvir/ritonavir in reducing the risk of severe outcome in patients with SARS-CoV-2 infection: a real-life full-matched case-control study (SAVALO Study)
Treatment with N/r has proven effective in reducing mortality among outpatients with SARS-CoV-2 infection during several omicron variant surges. The beneficial effect of N/r treatment in reducing progression is more pronounced in unvaccinated patients.
Authors
- Anna Borrelli (ORCID: https://orcid.org/0000-0002-2633-8507)
- Antonio Di Fusco
- Alessia D’Agostino (ORCID: https://orcid.org/0000-0002-4309-1083)
- Luigi Ametrano (ORCID: https://orcid.org/0000-0002-4181-4938)
- Nunzia Esposito (ORCID: https://orcid.org/0000-0002-7264-5014)
- Lidia Festa
- A. Iuliano (ORCID: https://orcid.org/0000-0001-6087-9633)
- Matteo Lorito (ORCID: https://orcid.org/0000-0002-0529-3709)
- Giulio Viceconte (ORCID: https://orcid.org/0000-0003-3989-2520)
- Fausto Minervini
- Giuseppe Longo (ORCID: https://orcid.org/0000-0003-1582-3125)
- Gaia Di Troia
- Federica Licciardi
- Letizia Cattaneo
- Antonio Riccardo Buonomo (ORCID: https://orcid.org/0000-0002-4378-8366)
- Mariarosaria Cotugno
- Ferdinando Calabria (ORCID: https://orcid.org/0000-0003-3774-6802)
- Laura Reynaud
- Nicola Schiano Moriello (ORCID: https://orcid.org/0000-0001-8474-4776)
- Francesco Brizzi (ORCID: https://orcid.org/0000-0003-4181-8522)
- Mayte Forte (ORCID: https://orcid.org/0009-0004-1978-5677)
- Antonella Gesmundo
- Marina Sarno (ORCID: https://orcid.org/0000-0001-6892-7775)
- Stefano Susini (ORCID: https://orcid.org/0000-0002-2166-838X)
- M Chiariello (ORCID: https://orcid.org/0000-0001-8434-5177)
- Maria Michela Scirocco
- Agnese Giaccone (ORCID: https://orcid.org/0000-0003-4002-0930)
- Isabella Di Filippo (ORCID: https://orcid.org/0009-0008-0523-7441)
- Mariarosaria Faiella
- Giuseppe Portella (ORCID: https://orcid.org/0000-0001-8276-9769)
- Emanuela Zappulo (ORCID: https://orcid.org/0000-0002-7660-7939)
- Mariano Nobile (ORCID: https://orcid.org/0000-0003-0324-0125)
- Giulia Zumbo
- Riccardo Scotto (ORCID: https://orcid.org/0000-0002-0178-2986)
- Giovanni Di Filippo
- Alberto Enrico Maraolo (ORCID: https://orcid.org/0000-0002-7218-7762)
- Anastasia Tanzillo
- Emilia Trucillo
- Simona Mercinelli
- Dario Diana
- Giuseppina Muto
- Antonella Gallicchio
- Fabrizio Scordino
- Ludovica Fusco
- Ivan Gentile (ORCID: https://orcid.org/0000-0002-5199-8451)
- Biagio Pinchera (ORCID: https://orcid.org/0000-0002-8685-5434)
- Alessia Sardanelli
- Grazia Tosone (ORCID: https://orcid.org/0000-0002-9703-8739)
- Maria Silvitelli
- Irene Irace
- Francesco Antimo Alfè
- Daria Pietroluongo
- Giuseppe Castaldo (ORCID: https://orcid.org/0000-0002-4036-0874)
- Simone Severino
- Gianpaolo Gargiulo
- Mariarosaria Chiariello
- Noemi De Felice
- Maria Foggia
- C. Iervolino
- Federica Cuccurullo
- Ilaria Vecchietti
- Federico Di Panni
Institutions
- Ospedale D. Cotugno (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12879-024-10303-5
- Citations
- 3
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Regione Campania