The impact of a short-term high-fat diet on coagulation function in a mouse model and its role in exacerbating concanavalin A-induced liver injury
Consuming a HFD in short-term can enhance primary and secondary hemostasis, thereby increasing the risk of thrombosis. These conditions are presumed to be a risk factor that exacerbates Con A-induced liver injury. The findings provide insight into early intervention strategies for chronic liver diseases, such as MASLD and MASH.
Authors
- Shun Otsuka (ORCID: https://orcid.org/0000-0003-1832-9472)
- Yuki Tamaki (ORCID: https://orcid.org/0009-0002-8814-2515)
- Tomiko Yakura (ORCID: https://orcid.org/0000-0002-2605-8396)
- Eri Nanizawa (ORCID: https://orcid.org/0000-0002-6190-7875)
- Munekazu Naito
- Naoyuki Hatayama
Institutions
- Tokyo Medical University (JP)
- Aichi Medical University (JP)
Publication Details
- Journal
- BMC Nutrition
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s40795-024-00966-3
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Japan Society for the Promotion of Science