Association between choroid plexus volume and cognitive function in community-dwelling older adults without dementia: a population-based cross-sectional analysis
CP volume may be a highly sensitive imaging marker of cognitive decline in community-dwelling older adults without dementia, as it is linked to cognitive decline independently of brain parenchyma and CSF volumes. Our findings emphasize the importance of investigating CP volume increase to maintain cognitive function in older individuals. Accordingly, further longitudinal studies are required.
Authors
- Ryuji Fukuhara (ORCID: https://orcid.org/0000-0003-0949-4505)
- Asuka Koyama (ORCID: https://orcid.org/0000-0002-4559-1460)
- Seiji Yuuki (ORCID: https://orcid.org/0000-0003-0925-7964)
- Kazuhiro Yoshiura (ORCID: https://orcid.org/0009-0008-3930-2985)
- Naoto Kajitani (ORCID: https://orcid.org/0000-0001-7245-9206)
- Naoko Tsunoda
- Yusuke Miyagawa (ORCID: https://orcid.org/0000-0001-9905-177X)
- Tomohisa Ishikawa (ORCID: https://orcid.org/0000-0002-4971-6830)
- Takashi Suehiro (ORCID: https://orcid.org/0000-0002-1477-4280)
- Manabu Ikeda (ORCID: https://orcid.org/0000-0003-0730-5774)
- Shuken Boku (ORCID: https://orcid.org/0000-0003-3089-3201)
- Yosuke Hidaka (ORCID: https://orcid.org/0009-0004-6735-8688)
- Kazunari Ishii (ORCID: https://orcid.org/0000-0001-6601-952X)
- Minoru Takebayashi (ORCID: https://orcid.org/0000-0001-9962-8444)
- Mamoru Hashimoto
- Kazuki Honda
Institutions
- Kagoshima University (JP)
- Kumamoto Gakuen University (JP)
- National Center for Geriatrics and Gerontology (JP)
- Kindai University (JP)
- Kumamoto University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12987-024-00601-0
- Citations
- 15
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 4.02
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science