Validation of the Histamine‐ and Heat‐Induced Axon‐Reflex Flare Response in a Nonselected Population of People With Type 1 Diabetes

The histamine-induced ARF response is a valid marker for small fiber neuropathy even in nonselected populations with diabetes with good agreement with established markers and can thus be used for evaluation of C-fiber function. The lack of correlation with the heat-induced ARF may be due to insufficient heating.

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Publication Details

Journal
Muscle & Nerve
Published
2024-12-18
DOI
https://doi.org/10.1002/mus.28325
Primary Topic
Thermoregulation and physiological responses
Type
article
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article

Validation of the Histamine‐ and Heat‐Induced Axon‐Reflex Flare Response in a Nonselected Population of People With Type 1 Diabetes

Silvia Lo Vecchio, Johan Røikjer, Niels Ejskjær, Carsten Dahl Mørch et al.
Muscle & Nerve
Thermoregulation and physiological responses
article

Validation of the Histamine‐ and Heat‐Induced Axon‐Reflex Flare Response in a Nonselected Population of People With Type 1 Diabetes

Silvia Lo Vecchio, Johan Røikjer, Niels Ejskjær, Carsten Dahl Mørch, Ken Steffen Frahm, Mette Krabsmark Borbjerg, A. E. Larsen, Pernille Tind
article en

Abstract

The histamine-induced ARF response is a valid marker for small fiber neuropathy even in nonselected populations with diabetes with good agreement with established markers and can thus be used for evaluation of C-fiber function. The lack of correlation with the heat-induced ARF may be due to insufficient heating.

Muscle & NerveVol. 71(2)
Steno Diabetes Centers (DK), Aalborg University Hospital (DK), Aalborg University (DK)
Good health and well-being
Openalex Percentile: Top 67%
Thermoregulation and physiological responses
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