Development of a thrombin-antithrombin complex detection kit and study in venous thromboembolism complicated by cervical cancer
Our developed TAT test kit has excellent performance and low cost, making it a clinically valuable tool for widespread use. Elevated TAT levels have significant predictive value for thrombosis occurrence in cervical cancer patients. The combination of t-PAIC, TM, TAT, PIC, D-dimer(D-D), and FDP markers is superior to using a single marker for diagnosing VTE in patients with malignant tumors. Screening cervical cancer patients for the six markers is essential to aid in active prophylaxis, determine optimal treatment timing, and implement nursing interventions to improve prognosis, reduce venous thrombosis incidence and mortality, and prolong survival time.
Authors
- Zhixian Lu
- Xuan Huang (ORCID: https://orcid.org/0000-0002-3670-9869)
- Yanru Qiu
- Shuang Han (ORCID: https://orcid.org/0000-0002-9689-2175)
- Yu Ji
Institutions
- Jiangnan University (CN)
Publication Details
- Journal
- BMC Biotechnology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12896-024-00930-w
- Citations
- 7
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 3.85
Funders
- Jiangnan University
- Shanghai Key Laboratory of Molecular Imaging
- Wuxi Health and Family Planning Commission