Development of a thrombin-antithrombin complex detection kit and study in venous thromboembolism complicated by cervical cancer

Our developed TAT test kit has excellent performance and low cost, making it a clinically valuable tool for widespread use. Elevated TAT levels have significant predictive value for thrombosis occurrence in cervical cancer patients. The combination of t-PAIC, TM, TAT, PIC, D-dimer(D-D), and FDP markers is superior to using a single marker for diagnosing VTE in patients with malignant tumors. Screening cervical cancer patients for the six markers is essential to aid in active prophylaxis, determine optimal treatment timing, and implement nursing interventions to improve prognosis, reduce venous thrombosis incidence and mortality, and prolong survival time.

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Publication Details

Journal
BMC Biotechnology
Published
2024-12-18
DOI
https://doi.org/10.1186/s12896-024-00930-w
Citations
7
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
3.85

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article

Development of a thrombin-antithrombin complex detection kit and study in venous thromboembolism complicated by cervical cancer

Zhixian Lu, Xuan Huang, Yanru Qiu, Shuang Han et al.
7 citations
BMC Biotechnology
Venous Thromboembolism Diagnosis and Management
3.85
article

Development of a thrombin-antithrombin complex detection kit and study in venous thromboembolism complicated by cervical cancer

Zhixian Lu, Xuan Huang, Yanru Qiu, Shuang Han, Yu Ji
article en
7 citations

Abstract

Our developed TAT test kit has excellent performance and low cost, making it a clinically valuable tool for widespread use. Elevated TAT levels have significant predictive value for thrombosis occurrence in cervical cancer patients. The combination of t-PAIC, TM, TAT, PIC, D-dimer(D-D), and FDP markers is superior to using a single marker for diagnosing VTE in patients with malignant tumors. Screening cervical cancer patients for the six markers is essential to aid in active prophylaxis, determine optimal treatment timing, and implement nursing interventions to improve prognosis, reduce venous thrombosis incidence and mortality, and prolong survival time.

BMC BiotechnologyVol. 24(1)
Jiangnan University (CN)
Jiangnan University, Shanghai Key Laboratory of Molecular Imaging, Wuxi Health and Family Planning Commission
Good health and well-being
Openalex Percentile: Top 6%
Venous Thromboembolism Diagnosis and Management
3.85
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Development of a thrombin-antithrombin complex detection kit and study in venous thromboembolism complicated by cervical cancer — Zhixian Lu, Xuan Huang, et al. · BMC Biotechnology (2024) | TGRS Research Map | TGRS