Comparative analysis of metabolic characteristics and prognostic stratification of HER2-low and HER2-zero breast cancer using 18F-FDG PET/CT imaging
Our study demonstrated the HR-positive HER2-low breast cancer exhibited a particularity in glucose metabolic profile. Additionally, HER2-zero patients with elevated metabolism were associated with inferior prognosis and warranted careful attention in clinical evaluations.
Authors
- Lei Yin (ORCID: https://orcid.org/0000-0002-9741-7376)
- Linlin Ma (ORCID: https://orcid.org/0000-0002-4716-5158)
- Yulong Chen (ORCID: https://orcid.org/0000-0003-4754-3056)
- Hongjin Liu (ORCID: https://orcid.org/0000-0001-5625-2395)
- Jinzhi Chen (ORCID: https://orcid.org/0000-0003-4131-771X)
- Jingming Ye
- Ling Xu (ORCID: https://orcid.org/0000-0002-9236-3014)
- Liang Li (ORCID: https://orcid.org/0000-0002-6836-042X)
- Meng Liu (ORCID: https://orcid.org/0000-0002-6960-3163)
- Caixia Wu (ORCID: https://orcid.org/0000-0002-3517-8568)
- Xiaojuan Zhu (ORCID: https://orcid.org/0000-0002-3782-1342)
- Yuan Gao (ORCID: https://orcid.org/0000-0002-9091-0563)
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- Cancer Imaging
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s40644-024-00812-6
- Citations
- 5
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- Peking University First Hospital
- National Natural Science Foundation of China
- Peking University