Eight-fold increased COVID-19 mortality in autosomal dominant tubulointerstitial kidney disease due to MUC1 mutations: an observational study
Individuals with ADTKD-MUC1 are at an eight-fold increased risk of COVID-19 mortality vs. ADTKD-UMOD individuals. Haplo-insufficient production of mucin-1 may be responsible.
Authors
- Tomáš Zima (ORCID: https://orcid.org/0000-0001-8518-6972)
- Michal Pohludka (ORCID: https://orcid.org/0000-0001-7199-1102)
- Martina Živná (ORCID: https://orcid.org/0000-0003-1968-824X)
- Alena Vrbacká
- Holly R. Mabillard (ORCID: https://orcid.org/0000-0001-6725-7570)
- Claudia Izzi (ORCID: https://orcid.org/0000-0001-6253-3185)
- Kendrah Kidd (ORCID: https://orcid.org/0000-0003-3771-0949)
- Constantinos Deltas (ORCID: https://orcid.org/0000-0001-5549-9169)
- Petr Vyleťal (ORCID: https://orcid.org/0000-0002-9357-1237)
- Christoforos Stavrou
- Gregory Papagregoriou (ORCID: https://orcid.org/0000-0002-2440-9789)
- John Andrew Sayer (ORCID: https://orcid.org/0000-0003-1881-3782)
- Kateřina Hodaňová (ORCID: https://orcid.org/0000-0001-9172-9945)
- Lenka Piherová (ORCID: https://orcid.org/0000-0001-7917-6364)
- Abbigail Taylor
- Martin Radina (ORCID: https://orcid.org/0009-0001-0027-8665)
- Eric Olinger (ORCID: https://orcid.org/0000-0003-1178-7980)
- Elhussein A. Elhassan
- Anthony J. Bleyer (ORCID: https://orcid.org/0000-0002-2804-5273)
- Peter J. Conlon (ORCID: https://orcid.org/0000-0001-6772-9531)
- Victoria Robins
- Stanislav Kmoch (ORCID: https://orcid.org/0000-0002-6239-707X)
- Drahomíra Springer (ORCID: https://orcid.org/0000-0003-4756-0585)
- Richard Edmund Hogan
- Lauren Martin (ORCID: https://orcid.org/0009-0003-6450-5411)
- Adrienne H. Williams
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- Royal College of Surgeons in Ireland (IE)
- Charles University (CZ)
- Paphos General Hospital (CY)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- Beaumont Hospital (IE)
- University of Cyprus (CY)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- DNA Solutions (United States) (US)
- NIHR Newcastle Biomedical Research Centre (GB)
- Medirex Group Academy (SK)
- Wake Forest University (US)
- University of Brescia (IT)
- Newcastle University (GB)
Publication Details
- Journal
- BMC Nephrology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12882-024-03896-1
- Citations
- 1
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Royal College of Surgeons of England
- Ministerstvo Zdravotnictví Ceské Republiky
- National Institute of Diabetes and Digestive and Kidney Diseases