Continuous prediction for tumor mutation burden based on transcriptional data in gastrointestinal cancers
TMB correlates with clinicopathological parameters in gastrointestinal carcinoma, and patients with high TMB have higher levels of immune infiltration. In addition, the DNN model based on 31 genes predicts TMB of gastrointestinal tumors in a high accuracy.
Authors
- Beibei Hu (ORCID: https://orcid.org/0000-0002-6396-3854)
- Xuren Sun (ORCID: https://orcid.org/0000-0003-1435-6182)
- Yi Bai (ORCID: https://orcid.org/0009-0006-5064-1596)
- Jialin Zhu (ORCID: https://orcid.org/0000-0002-3126-2148)
- Guohui Yin
Institutions
- Central South University (CN)
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- BMC Medical Informatics and Decision Making
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12911-024-02794-8
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.13