Identification of key necroptosis-related genes and immune landscape in patients with immunoglobulin A nephropathy
In summary, we identified 7 hub necroptosis-associated genes, which can be used as potential genetic biomarkers for IgAN prediction and treatment. Four drugs were predicted as the potential therapeutic solutions. Collectively, we provided insights into the necroptosis-related mechanisms and treatment of IgAN at the transcriptome level.
Authors
- Dechao Xu (ORCID: https://orcid.org/0000-0002-4241-4880)
- Panfeng Feng (ORCID: https://orcid.org/0000-0001-7817-7971)
- Ziyu Liu (ORCID: https://orcid.org/0000-0001-8824-9481)
- Xiaorong Wang (ORCID: https://orcid.org/0000-0002-1912-3890)
- Ruikun Hu (ORCID: https://orcid.org/0000-0001-8148-6134)
- Hou H
- Ming Yang (ORCID: https://orcid.org/0000-0001-8013-5148)
- Jingyu Li (ORCID: https://orcid.org/0009-0008-2211-4021)
Institutions
- Tongji University (CN)
- Nantong University (CN)
- Nantong Maternity and Child Health Hospital (CN)
- Affiliated Hospital of Nantong University (CN)
- Shanghai Changzheng Hospital (CN)
- Second People's Hospital of NanTong (CN)
- Second Affiliated Hospital of Nantong University
Publication Details
- Journal
- BMC Nephrology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12882-024-03885-4
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- National Natural Science Foundation of China