Role of TLR4 activation and signaling in bone remodeling, and afferent sprouting in serum transfer arthritis

These results demonstrated a complex chronic allodynia phenotype associated with TLR4 in microglia and monocytic cell lineages, and a parallel spinal TLR4 activation. However, TLR4 is dispensable for the development of peripheral nerve sprouting in this model.

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Publication Details

Journal
Arthritis Research & Therapy
Published
2024-12-18
DOI
https://doi.org/10.1186/s13075-024-03424-4
Citations
1
Primary Topic
Immune Response and Inflammation
Type
article
Field-Weighted Citation Impact
0.24

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article

Role of TLR4 activation and signaling in bone remodeling, and afferent sprouting in serum transfer arthritis

Juan Miguel Jiménez‐Andrade, Gilson Gonçalves dos Santos, Peter Pham, Mariana E. Candanedo-Quiroz et al.
1 citations
Arthritis Research & Therapy
Immune Response and Inflammation
0.24
article

Role of TLR4 activation and signaling in bone remodeling, and afferent sprouting in serum transfer arthritis

Juan Miguel Jiménez‐Andrade, Gilson Gonçalves dos Santos, Peter Pham, Mariana E. Candanedo-Quiroz, Yury I. Miller, Lauriane Delay, Tony L. Yaksh, Bronwen Drummond, Enriqueta Muñoz‐Islas, Maripat Corr, Chao‐Chin Hsu, Juliana M. Navia‐Pelaez, Andrés Cárdenas, Julia Paes Lemes, Gwendalynn Stilson
article en
1 citations

Abstract

These results demonstrated a complex chronic allodynia phenotype associated with TLR4 in microglia and monocytic cell lineages, and a parallel spinal TLR4 activation. However, TLR4 is dispensable for the development of peripheral nerve sprouting in this model.

Arthritis Research & TherapyVol. 26(1)
University of California San Diego (US), Autonomous University of Tamaulipas (MX)
National Institutes of Health, National Institute of Neurological Disorders and Stroke
Openalex Percentile: Top 39%
Immune Response and Inflammation
0.24
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Role of TLR4 activation and signaling in bone remodeling, and afferent sprouting in serum transfer arthritis — Juan Miguel Jiménez‐Andrade, Gilson Gonçalves dos Santos, et al. · Arthritis Research & Therapy (2024) | TGRS Research Map | TGRS