Effect of changes in skin properties due to diabetes mellitus on the titration period of transdermal fentanyl: single-center retrospective study and diabetic animal model study
Our results suggest that the steady state of transdermally administered fentanyl is reached sooner in cancer patients with DM as a comorbidity. Earlier pain assessment and dose adjustment may be possible in these patients.
Authors
- Kazuhiro Ogai (ORCID: https://orcid.org/0000-0002-3462-9320)
- Yusuke Hara (ORCID: https://orcid.org/0000-0001-7271-3454)
- Arimi Fujita (ORCID: https://orcid.org/0000-0001-6557-8514)
- Kei Tsukui (ORCID: https://orcid.org/0009-0008-4468-4738)
- Yoshihiro Tokudome (ORCID: https://orcid.org/0000-0001-9269-9901)
- Tomoko Akase (ORCID: https://orcid.org/0000-0002-4768-2999)
- Yukio Kato (ORCID: https://orcid.org/0000-0001-8135-5679)
- Hiroko Makihara
- Yoshimichi Sai (ORCID: https://orcid.org/0000-0003-2954-1532)
- Makiko Takabayashi
- Yuriko Ito
- Tsutomu Shimada (ORCID: https://orcid.org/0000-0003-2552-4348)
- S. Mizuno
- Takahiro Kawakami (ORCID: https://orcid.org/0000-0002-1019-2304)
Institutions
- Kanazawa University (JP)
- Kagoshima University (JP)
- Saga University (JP)
- Ishikawa Prefectural Nursing University (JP)
- Kanazawa University Hospital (JP)
- Kanazawa Medical University Hospital (JP)
- Tokyo Women's Medical University (JP)
- Yokohama City University (JP)
Publication Details
- Journal
- Journal of Pharmaceutical Health Care and Sciences
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s40780-024-00402-5
- Citations
- 1
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- Kanazawa University
- Japan Society for the Promotion of Science
- Japan Science and Technology Agency