Response of human metabolism to ultra-low and high nicotine cigarettes based on urine metabolomics and bioinformatic analysis
Cigarettes with different nicotine content may alter the metabolism of smokers. A total of 1150 significantly different metabolites were identified between the HN and LN groups, which were mainly enriched in ABC transporters, protein kinase G (cGMP)-protein kinase G (PKG) signaling pathway, caffeine metabolism, and arginine biosynthesis pathways.
Authors
- Hongzhi Shi (ORCID: https://orcid.org/0000-0002-2400-0721)
- Chunting Yang
- Yuanyuan Zhao (ORCID: https://orcid.org/0000-0002-4838-7430)
- Mengyue Zhang (ORCID: https://orcid.org/0009-0006-5635-730X)
- Lingling Gao (ORCID: https://orcid.org/0000-0003-2944-1865)
Institutions
- Henan Academy of Agricultural Sciences (CN)
- Henan Agricultural University (CN)
Publication Details
- Journal
- Tobacco Induced Diseases
- Published
- 2024-12-18
- DOI
- https://doi.org/10.18332/tid/196677
- Citations
- 1
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Henan Agricultural University
- Science and Technology Department of Henan Province