Using hierarchical drift diffusion models to elucidate computational mechanisms of reduced reward sensitivity in adolescent major depressive disorder
Our findings suggest that reduced reward sensitivity and slower evidence accumulation during reward learning may serve as potential indicators of anhedonia in adolescents with MDD. These findings provided crucial insights into the dysregulated positive affect model, underscoring a dysfunctional reward system as a key factor in anhedonia developmental psychopathology in depression.
Authors
- Jingbo Gong (ORCID: https://orcid.org/0000-0002-4880-0934)
- Lei Shen (ORCID: https://orcid.org/0000-0003-0307-696X)
- Chao Yan (ORCID: https://orcid.org/0000-0002-0327-9321)
- Zhenghui Yi (ORCID: https://orcid.org/0000-0003-3546-3219)
- Ya-xin Hu
- Qinyu Lv
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Mental Health Center (CN)
- Shanghai Changning Mental Health Center (CN)
- East China Normal University (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12888-024-06353-3
- Citations
- 8
- Primary Topic
- Mental Health Research Topics
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Natural Science Foundation of China
- East China Normal University