Quantitative Assessment of Baseline Serum HDL-C to Predict Gout Flares During Urate-Lowering Therapy Initiation: A Prospective Cohort Study
Patients with gout presented a negative linear relationship between serum HDL-C and gout flares. Together with common clinical indicators, the AUC for gout flare prediction increased to 0.75. For patients with gout, remaining serum HDL-C level above 1.15 mmol/L may reduce the risk of gout flares.
Authors
- Jiang Chang (ORCID: https://orcid.org/0000-0001-8551-9458)
- Yuwei He (ORCID: https://orcid.org/0000-0002-5107-5323)
- Xinde Li (ORCID: https://orcid.org/0000-0002-1529-4537)
- Qi Han (ORCID: https://orcid.org/0000-0002-6974-0344)
- Jie Lü (ORCID: https://orcid.org/0000-0003-2886-8285)
- Lingling Cui (ORCID: https://orcid.org/0000-0003-1367-5851)
- Maichao Li
- Ying Chen (ORCID: https://orcid.org/0000-0001-6180-1600)
- Xiaoqing Zhang (ORCID: https://orcid.org/0000-0002-0521-8231)
- Changgui Li (ORCID: https://orcid.org/0000-0002-4622-3731)
- Cheng Zan
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qinghai Provincial Peoples Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jir.s493376
- Citations
- 2
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.68
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province