Prenatal diagnosis and molecular cytogenetic analysis of pure chromosome 10p15.3 microdeletion using chromosomal microarray analysis
The present study is the first to report two cases of pure terminal chromosome 10p15.3 microdeletion syndrome in fetuses, offering valuable insights for the prenatal diagnosis of 10p15.3 microdeletion syndrome. Further, it is the first to describe mild clinical features, specifically limited to language impairment, in a patient with 10p15.3 microdeletion syndrome.
Authors
- Na Zhang (ORCID: https://orcid.org/0000-0001-9805-6026)
- Yue Chen (ORCID: https://orcid.org/0000-0003-4863-0864)
- Jianlong Zhuang
- Xinying Chen (ORCID: https://orcid.org/0000-0002-5278-1238)
- Nan Huang
Institutions
- Quanzhou Normal University (CN)
- Fujian Women and Children Hospital (CN)
- The 180th Hospital of PLA (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12920-024-02063-7
- Primary Topic
- Genomic variations and chromosomal abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Huaqiao University
- Science and Technology Bureau of Quanzhou