Sex-Biased CD3ζ 3ʹ-UTR SNP Increased Incidence Risk in Aplastic Anemia
This study first identified sex-specific CD3ζ 3'-UTR SNPs that were associated with risk of AA. Our data also demonstrated that rs3738212 could upregulate CD3ζ protein level.
Authors
- Lixing Guo (ORCID: https://orcid.org/0009-0009-3211-0662)
- Xiaoen Liu (ORCID: https://orcid.org/0000-0002-4122-2641)
- Weifeng Luo (ORCID: https://orcid.org/0000-0002-0426-2951)
- Yankai Xiao (ORCID: https://orcid.org/0000-0003-2785-7867)
- Yangqiu Li (ORCID: https://orcid.org/0000-0002-0974-4036)
- Bo Li (ORCID: https://orcid.org/0000-0002-9597-1306)
- Yan Li (ORCID: https://orcid.org/0000-0001-6018-6538)
- Yuping Zhang (ORCID: https://orcid.org/0000-0003-1055-2071)
- Jing Lai
- Fang Su (ORCID: https://orcid.org/0000-0002-8780-6095)
Institutions
- Xinjiang Medical University (CN)
- Jinan University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- Guangzhou Blood Center (CN)
- Guangzhou First People's Hospital (CN)
- Xi’an Children’s Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Journal of General Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/ijgm.s489870
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Jinan University
- Science and Technology Planning Project of Guangdong Province
- Basic and Applied Basic Research Foundation of Guangdong Province