Evaluation of the antifungal and antibacterial activities of plant extracts of the genera Centaurea papposa bleu and Hypochaeris laevigata var hipponensis

Hypochaeris and Centaurea are endemic plants belonging to the Asteraceae family, localized through out Algeria for (Hypochaeris Laevigata Var) and as an Annaba guard coat for (Centaurea Papposa). Sounds Their richness in secondary metabolites led us to proceed to their extractions by methanol; then the methanolic extract is fractionated using solvents of increasing polarity. The objective of this study is the evaluation of the antibacterial and antifungal activity of the extracts: Dichloromethane, N-butanol and Ethylacetate, using the method of diffusion by discs for the antibacterial activities on five strains with Gram - and Gram +, and the method of wells for antifungal activity on three phytopathogenic fungal strains. The results revealed that the bacterial strains are very sensitive to the extract Dichloromethane (Hypochaeris Laevigata Var) and Ethylacetate (Centaurea Papposa) with significant areas of inhibition and the fungal strains are sensitive to N-butanol (Hypochaeris Laevigata Var) and Dichloromethane (Centaurea Papposa) extracts. The two plants studied and according to their antibacterial and antifungal effects are rich in secondary metabolites which gives them an important therapeutic and medicinal value. The results of the present study provide a general overview of the antibacterial and antifungal potential of extracts from these plants. So studies on these extracts deserve to be continued.