Heritable Burden of Community Sudden Death by Autopsy and Molecular Phenotyping for Precision Genotype Correlation
In this 7-year countywide study, 2% of total sudden deaths and 2.5% of confirmed SCDs had identifiable genetic cause, corrected for genotype-phenotype concordance. These results do not support routine genetic testing for community sudden deaths, particularly without autopsy.
Authors
- James W. Salazar
- Matthew Yee (ORCID: https://orcid.org/0000-0001-5354-9820)
- Zian H. Tseng (ORCID: https://orcid.org/0000-0001-5996-4099)
- W. Patrick Devine (ORCID: https://orcid.org/0000-0003-4634-8830)
- Julianne Wojciak
- Jean Feng (ORCID: https://orcid.org/0000-0003-2041-3104)
- Ellen Moffatt (ORCID: https://orcid.org/0000-0002-3804-3116)
- David Eik
- Andrew J. Connolly (ORCID: https://orcid.org/0000-0002-0660-3270)
- Brielle Kinkead
Institutions
- Office of Chief Medical Examiner (US)
- University of California, San Francisco (US)
Publication Details
- Journal
- JACC. Clinical electrophysiology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1016/j.jacep.2024.10.027
- Citations
- 1
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- National Heart, Lung, and Blood Institute