Levofloxacin Preventive Treatment in Children Exposed to MDR Tuberculosis
Although preventive treatment with levofloxacin led to a lower incidence of tuberculosis than placebo among children with household exposure to MDR tuberculosis, the difference was not significant. (Supported by Unitaid and others; TB-CHAMP ISRCTN Registry number, ISRCTN92634082.).
Authors
- Hendrik Simon Schaaf (ORCID: https://orcid.org/0000-0001-5755-4133)
- Charlotte Layton
- Rebecca Turner (ORCID: https://orcid.org/0000-0001-7194-5464)
- Charlotte McGowan
- Diana M. Gibb (ORCID: https://orcid.org/0000-0002-9738-5490)
- Susan E. Purchase (ORCID: https://orcid.org/0000-0002-9629-5952)
- Suzanne Staples (ORCID: https://orcid.org/0000-0002-9049-8070)
- Anthony J. Garcia‐Prats (ORCID: https://orcid.org/0000-0002-9280-1950)
- Samukelisiwe Nyamathe
- Elizabeth Batist
- Lisa Frigati (ORCID: https://orcid.org/0000-0002-4097-3128)
- Francesca Conradie (ORCID: https://orcid.org/0000-0002-0194-3559)
- Neil Alexander Martinson (ORCID: https://orcid.org/0000-0002-0184-5705)
- James A. Seddon (ORCID: https://orcid.org/0000-0002-2296-2302)
- Lee Fairlie (ORCID: https://orcid.org/0000-0001-5327-1734)
- Anneke C Hesseling
- Anne‐Marie Demers
- Trinh Duong (ORCID: https://orcid.org/0009-0003-1052-0827)
- Joanna Brigden
Institutions
- Johns Hopkins University (US)
- Stellenbosch University (ZA)
- University College London (GB)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1056/nejmoa2314318
- Citations
- 45
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 17.51
Funders
- Medical Research Council