Vagus nerve stimulation in treatment-resistant depression: A one-year, randomized, sham-controlled trial
Percent time in MADRS response did not distinguish the treatment groups, but on multiple instruments time in response and PR showed a positive treatment effect. VNS was found safe and effective in participants with marked TRD.
Authors
- Mark S. George (ORCID: https://orcid.org/0000-0003-1767-1815)
- Laura Yates (ORCID: https://orcid.org/0000-0002-7963-625X)
- Matthew Berger (ORCID: https://orcid.org/0000-0003-2697-3516)
- Matthew Macaluso (ORCID: https://orcid.org/0000-0001-6856-6236)
- Ziad Nahas (ORCID: https://orcid.org/0000-0002-8391-5673)
- Mark T. Bunker (ORCID: https://orcid.org/0000-0001-5871-0687)
- A. John Rush (ORCID: https://orcid.org/0000-0003-2004-2382)
- Harold A. Sackeïm (ORCID: https://orcid.org/0000-0002-1107-4553)
- Rebecca M. Allen (ORCID: https://orcid.org/0000-0002-7880-6958)
- Mary Stedman
- Michael Banov
- Christopher Kriedt
- Brian J. Mickey (ORCID: https://orcid.org/0000-0002-7847-7680)
- Charles R. Conway (ORCID: https://orcid.org/0000-0001-6849-9416)
- Lucian Manu
- Ying-Chieh Lee (ORCID: https://orcid.org/0000-0002-5414-5497)
- Scott T. Aaronson (ORCID: https://orcid.org/0000-0001-7616-8801)
- Walter Duffy (ORCID: https://orcid.org/0009-0006-5261-9659)
- Patricio Riva‐Posse (ORCID: https://orcid.org/0000-0002-5887-0557)
- David L. Dünner
- Yvette I. Sheline (ORCID: https://orcid.org/0000-0002-6929-9659)
- Gustavo Alva (ORCID: https://orcid.org/0000-0001-9742-398X)
- John Zajecka (ORCID: https://orcid.org/0000-0001-8398-636X)
- João Quevedo (ORCID: https://orcid.org/0000-0003-3114-6611)
- Ivan Cichowicz
- Olivia Shy
- Quyen Tran
- Charles M. Gordon (ORCID: https://orcid.org/0000-0001-7733-9342)
- Mohd Azfar Malik
Institutions
- University of Minnesota (US)
- Emory University (US)
- Medical University of South Carolina (US)
- Washington University in St. Louis (US)
- University of Missouri–St. Louis (US)
- University of Utah (US)
- Huntsman Cancer Institute (US)
- University of Alabama at Birmingham (US)
- Psychiatric Medicine Associates (US)
- Stony Brook School (US)
- Sheppard Pratt Health System (US)
- Ophthalmology Consultants (US)
- Alivation (United States) (US)
- Applied Technical Services (United States) (US)
- Duke-NUS Medical School (SG)
- LivaNova (United Kingdom) (GB)
- Community Counseling Services (US)
- Ralph H. Johnson VA Medical Center (US)
- Stedman Clinical Trials (US)
- ATP Clinical Research (United States) (US)
- Center for Anxiety and Depression (US)
- The University of Texas Health Science Center (US)
- Stony Brook University (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Brain stimulation
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1016/j.brs.2024.12.1191
- Citations
- 25
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 6.19
Funders
- Washington University in St. Louis
- Carilion Clinic
- LivaNova