Analysis of transcriptomic data reveals the landscape of cholesterol metabolism in prostate cancer and impact of related signature on survival
We demonstrated the comprehensive role of cholesterol metabolism in PCa. Using the risk index, we could predict the prognosis, TME infiltration and response to chemotherapy/immunotherapy of PCa. Better understanding and evaluating the cholesterol metabolism could aid in precision medicine and promoting prognosis of PCa.
Authors
- Qi‐Dong Xia (ORCID: https://orcid.org/0000-0002-2278-1122)
- Si-Yang Ma
- Ye An (ORCID: https://orcid.org/0000-0003-0580-203X)
- Jian‐Xuan Sun (ORCID: https://orcid.org/0000-0003-2667-1200)
- Chen‐Qian Liu
- Jin‐Zhou Xu (ORCID: https://orcid.org/0000-0002-2696-2238)
- Mengyao Xu
- Shaogang Wang (ORCID: https://orcid.org/0000-0002-3206-1495)
Institutions
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1007/s12672-024-01658-x
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- National Natural Science Foundation of China