Early detection of colorectal cancer using aberrant circulating cell-free mitochondrial DNA fragmentomics
In conclusion, based on aberrant ccf-mtDNA fragmentomic features, a novel and non-invasive approach was established for the detection of patients with early-stage CRC or AA, with high performance.
Authors
- Jinliang Xing (ORCID: https://orcid.org/0000-0002-7010-1822)
- Kaixiang Zhou (ORCID: https://orcid.org/0000-0003-4210-6711)
- Lin Guo (ORCID: https://orcid.org/0000-0002-1277-3954)
- Renquan Lu (ORCID: https://orcid.org/0000-0003-3291-5742)
- Huanqin Zhang
- Zhiyun Gong (ORCID: https://orcid.org/0000-0002-2071-3150)
- Wenjie Guo (ORCID: https://orcid.org/0000-0002-6484-4777)
- Bing-Rong Liu (ORCID: https://orcid.org/0000-0001-6101-8675)
- Fan Peng (ORCID: https://orcid.org/0009-0002-2886-1593)
- Deliang Li (ORCID: https://orcid.org/0000-0001-9367-8686)
- Xu Guo (ORCID: https://orcid.org/0000-0003-4902-8859)
- Huanmin Jiao
- Siyuan Wang (ORCID: https://orcid.org/0000-0001-6550-4064)
- Yang Liu (ORCID: https://orcid.org/0009-0002-7318-9783)
- Miao Dang
Institutions
- Fudan University Shanghai Cancer Center (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Gut
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1136/gutjnl-2024-333533
- Citations
- 8
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.28
Funders
- National Natural Science Foundation of China